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Search Results for " bile acid "

20

Compounds

Cat No. Product Name Synonyms Targets
T2965 Deoxycholic acid Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic Endogenous Metabolite , GPCR19
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio...
T5077 Deoxycholic acid sodium salt Sodium deoxycholate,Sodium Desoxycholate Endogenous Metabolite , GPCR19
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T8153 Glycohyodeoxycholic acid Others , Endogenous Metabolite
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.
T19189 Allocholic acid Others
Allocholic acid is a fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. It is also a potent and specific stimulant of the adult olfactory system.
T0700 Ursodeoxycholic acid UDCA,Ursodiol Potassium Channel , Endogenous Metabolite
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T0022 Taurine 2-Aminoethanesulfonic acid LDL , Endogenous Metabolite , Autophagy
Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.
T31964 Glycolithocholic acid Lithocholic acid glycine conjugate,Lithocholylglycine Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
T13502 3-Oxo-5β-cholanoic acid Dehydrolithocholic acid ROR
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd: 1.13 μM)...
T29078 Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium FXR , Endogenous Metabolite , GPCR19
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...
T13522 7-Ketolithocholic acid 3α-Hydroxy-7-oxo-5β-cholanic acid Endogenous Metabolite
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester...
T2968 Hyodeoxycholic acid NSC 60672,α-Hyodeoxycholic Acid,HDCA FXR , Endogenous Metabolite , GPCR19
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
T7428 SBI-115 GPCR19
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T4083 BAR501 BAR 501 GPCR19
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
TQ0252 BAR502 FXR , GPCR19 , Autophagy
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T4352 SB756050 SB-756050,SB 756050 GPCR19
SB756050 is a specific TGR5 agonist.
T8599 Betazole dihydrochloride Betazole hydrochloride Histamine Receptor
Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor.
T11515 Gut restricted-7 GR-7 Potassium Channel
Gut restricted-7 (GR-7) (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.
T2A2481 Taurochenodeoxycholic Acid Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine Apoptosis , TNF , Caspase , Endogenous Metabolite
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
TN2215 Taurochenodeoxycholic acid sodium Sodium taurochenodeoxycholate Apoptosis , Endogenous Metabolite
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...
T1824 TGR5 Receptor Agonist GPCR19
TGR5 is a potent TGR5(GPCR19) agonist.

Compounds

Deoxycholic acid
T2965
Synonym: Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic
Target: Endogenous Metabolite, GPCR19
Deoxycholic acid sodium salt
T5077
Synonym: Sodium deoxycholate,Sodium Desoxycholate
Target: Endogenous Metabolite, GPCR19
glycohyodeoxycholic acid
T8153
Synonym:
Target: Others, Endogenous Metabolite
Allocholic acid
T19189
Synonym:
Target: Others
Ursodeoxycholic acid
T0700
Synonym: UDCA,Ursodiol
Target: Potassium Channel, Endogenous Metabolite
Taurine
T0022
Synonym: 2-Aminoethanesulfonic acid
Target: LDL, Endogenous Metabolite, Autophagy
Glycolithocholic acid
T31964
Synonym: Lithocholic acid glycine conjugate,Lithocholylglycine
Target: Others
3-Oxo-5β-cholanoic acid
T13502
Synonym: Dehydrolithocholic acid
Target: ROR
Ursodeoxycholic acid sodium
T29078
Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium
Target: FXR, Endogenous Metabolite, GPCR19
7-Ketolithocholic acid
T13522
Synonym: 3α-Hydroxy-7-oxo-5β-cholanic acid
Target: Endogenous Metabolite
Hyodeoxycholic acid
T2968
Synonym: NSC 60672,α-Hyodeoxycholic Acid,HDCA
Target: FXR, Endogenous Metabolite, GPCR19
SBI-115
T7428
Synonym:
Target: GPCR19
BAR501
T4083
Synonym: BAR 501
Target: GPCR19
BAR502
TQ0252
Synonym:
Target: FXR, GPCR19, Autophagy
SB756050
T4352
Synonym: SB-756050,SB 756050
Target: GPCR19
Betazole dihydrochloride
T8599
Synonym: Betazole hydrochloride
Target: Histamine Receptor
Gut restricted-7
T11515
Synonym: GR-7
Target: Potassium Channel
Taurochenodeoxycholic Acid
T2A2481
Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine
Target: Apoptosis, TNF, Caspase, Endogenous Metabolite
Taurochenodeoxycholic acid sodium
TN2215
Synonym: Sodium taurochenodeoxycholate
Target: Apoptosis, Endogenous Metabolite
TGR5 Receptor Agonist
T1824
Synonym:
Target: GPCR19
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TargetMol